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Homocysteine Factors

This is a practitioner-only product. Please arrange a telephone consultation with our health care practitioners to ensure this product is suitable for you.

  • Promotes cardiovascular health
  • Supports homocysteine metabolism
  • Provides a highly bioavailable combination of vitamin B6 , vitamin B12 , folate and betaine
  • Contains Metafolin® (L-5-MTHF), the naturally occurring, universally metabolized form of folate
  • Made with high-quality vegan ingredients backed by verifiable science


  • Ages 18 and up
  • Cardiovascular health support

Suggested Use

As a dietary supplement, take 1 capsule, 2 times daily, with meals.

Verifiable Science

Clinical studies show that folate, vitamin B12 , and vitamin B6 are vital in the metabolism of homocysteine. Vitamin B12 and folate (L-5-MTHF) are required by the enzyme that converts homocysteine back to methionine.1 Vitamin B6 is required in each of the two enzymatic reactions that convert homocysteine to cysteine.2 Betaine, in the form of trimethylglycine, is included in this supplement to promote the methylation of homocysteine.3 Homocysteine Factors provides vitamin B6 , vitamin B12 , folate and betaine, a highly bioavailable combination of nutrients integral to maintaining healthy homocysteine metabolism and cardiovascular health.



  1. Halsted CH, et al. Proc Natl Acad Sci USA. 2002 Jul 23;99(15):10072-7.
  2. den Heijer M, et al. Arterioscler Thromb Vasc Biol. 1998 Mar;18(3):356-61.
  3. Schwab U, et al. J Nutr. 2006 Jan;136(1):34-8.